The global tally of confirmed cases of the coronavirus-borne illness COVID-19 climbed above 221 million on Tuesday, with the U.S. now accounting for more than 40 million of that total, as the highly infectious delta variant continues to spread through the unvaccinated population.

The U.S. continues to lead the world by cases and fatalities and is averaging more than 1,500 deaths a day for the first time since March, according to a New York Times tracker. The seven-day average of new cases stood at 132,135 on Sunday, the tracker shows, while hospitalizations were averaging 101,747, or more than double the number recorded for Labor Day of 2020.

Despite pleas from public-health experts and a pickup in the daily pace of vaccinations since employers started mandating them for workers returning to offices, just 53% of the U.S. overall population is fully vaccinated, while 62.3% have received at least one dose of a two-dose regimen, according to the Centers for Disease Control and Prevention’s tracker.

That means 47% remain unvaccinated, putting themselves at risk of a lethal disease.

Read also: Fauci says mu variant isn’t an ‘immediate threat’ to U.S. as delta remains dominant coronavirus strain

Dr. Monica Gandhi, Professor of Medicine and Associate Division Chief of the Division of HIV, Infectious Diseases, and Global Medicine at UCSF/ San Francisco General Hospital, lamented the vaccine hesitancy that is frustrating experts.

‘I’m not happy that we have to get through it with some naturally immunity, I wish we had higher vaccination rates, like Ireland or Denmark,” she told MSNBC.

Denmark will lift all COVID restrictions on Sept. 10, with more than 70% of its citizens fully vaccinated, AFP recently reported. Denmark was one of the first countries to lock down in March 2020, when it closed schools and nonessential businesses.

Ireland, meanwhile, is planning to lift most of its COVID restrictions on Oct. 22 after enduring some of the strictest curbs in the world since late December. Ireland has also vaccinated more than 70% of its population of just over five million people.

Gandhi also addressed the new mu variant, which has become one of interest for the World Health Organization and which may have some resistance to the vaccines that have been authorized for approved for use. She explained that the variant appears to evade some antibodies, but said it would be hard to get a variant that completely evades the body’s T cell response, which is what protects people from severe disease.

Meanwhile, hospitals in Oregon and Idaho have joined other states that are rapidly running out of ICU beds, as new cases continue to rise, the Times reported. Hospitals in southern Oregon, where vaccination rates are lowest, are being especially hard hit.

Elsewhere, a Vietnamese man has been sentenced to five years in jail for breaking COVID-19 rules on movement, BBC News reported. A court found Le Van Tri guilty of “transmitting dangerous infectious diseases” to eight people, one of whom eventually died.

Cuba has become the first country in the world to start to vaccinate children above the age of two, using homegrown shots that have been recognized by the WHO, the South China Morning Post reported. The island of 11.2 million people is aiming to get all of its children inoculated before reopening schools.

Japan has ordered 150 million doses of the vaccine being developed by Novavax Inc.
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which has not yet been cleared by the U.S. Food and Drug Administration, The Japan Times reported. The vaccine with be made by Takeda Pharmaceutical Co.
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and is expected to be used as a booster and against new variants of the virus.

Italy is planning to offer third shots of vaccine to “clinically vulnerable” people later in September, the Guardian reported. “We’ll start in September with fragile patients like oncology and transplant patients,” Health Minister Roberto Speranza said.

Latest tallies

The global tally for the coronavirus-borne illness COVID-19 climbed above 221.2 million on Monday, while the death toll rose above 4.57 million, according to data aggregated by Johns Hopkins University.

The U.S. passed 40 million cases overnight and has 649,168 deaths.

India has the second highest death toll after the U.S. at 441,042 and is third by cases at 33 million, the JHU data shows.

Brazil has second highest death toll at 583,810 and has 20.9 million cases.

In Europe, Russia has 185,447 deaths, followed by the U.K. with 133,598.

China, where the virus was first discovered late in 2019, has had 107,256 confirmed cases and 4,848 deaths, according to its official numbers, which are widely held to be massively underreported.

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